From Tunja : minibuses leave every ten minutes. 1 hour / 6000 COP / 39 km
From Bogotá : Minibuses leave hourly in the morning and mid-afternoon. Los Libertades bus line has luxury buses that leave twice a day 4:40 am and 2:40 pm. The travel time is about 4 hours and it costs $20.000. 180 km.
From Chiquinquira: Vans leave hourly - approximately a 1 hour trip.
To reach the main plaza, take a right when you exit the terminal and head on that street Cra.9 for a couple blocks.
To combine a trip to the Salt Cathedral on the way to Villa de Leyva, take a bus to Zipaquira and then take a taxi to the Cathedral. Then take a taxi to Plaza de la Riena for a minibus to Chiquinquira. The minibus is operated by Transportes Reina Agencia and the departure location is at Carrera 36, 8-532.